What Are the Most Common Side Effects of Amlodipine? 12 Things to Watch Out For
Amlodipine is a calcium channel blocker commonly prescribed to treat high blood pressure (hypertension) and angina (chest pain). It relaxes blood vessels, making it easier for blood to flow.
Most people take amlodipine without serious problems, but side effects can occur. Many are mild and improve as your body adjusts to the medication.
1. Swollen Ankles or Feet
This is the most common side effect.
You may notice:
- Puffy ankles or feet
- Tight shoes or socks
- Swelling that is usually worse by the end of the day
Tell your healthcare professional if the swelling is persistent or bothersome.
2. Headache
Headaches can occur when starting amlodipine or after a dose increase. They often improve within the first few weeks.
3. Dizziness or Light-Headedness
As blood pressure falls, some people may feel:
- Dizzy when standing up
- Unsteady
- Faint
Standing up slowly can help reduce these symptoms.
4. Flushing
Some people experience:
- Warmth in the face
- Redness of the skin
- A sensation of heat
This is caused by widening of the blood vessels.
5. Feeling Tired
You may notice:
- Fatigue
- Reduced energy
- Feeling sleepy
If fatigue is severe or persistent, discuss it with your healthcare provider.
6. Heart Palpitations
Some people become more aware of their heartbeat or notice:
- A racing heartbeat
- Fluttering sensations
- Pounding in the chest
If palpitations are severe, persistent, or accompanied by chest pain or fainting, seek medical attention.
7. Nausea or Stomach Upset
Digestive symptoms can include:
- Nausea
- Abdominal discomfort
- Indigestion
These are usually mild.
8. Changes in Bowel Habits
Some people experience:
- Constipation
- Diarrhoea
Staying well hydrated and eating enough fibre may help.
9. Skin Rash or Itching
A mild rash or itching can occur. Seek urgent medical help if you develop:
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing
- A widespread blistering rash
These could indicate a serious allergic reaction.
10. Gum Overgrowth
Rarely, amlodipine can cause the gums to become swollen or overgrown.
Good oral hygiene and regular dental check-ups can help reduce this risk.
11. Low Blood Pressure
If blood pressure becomes too low, symptoms may include:
- Severe dizziness
- Fainting
- Weakness
- Blurred vision
Contact your healthcare professional if these symptoms occur.
12. Chest Pain That Worsens (Rare)
A small number of people may notice worsening chest pain or, very rarely, a heart attack when starting amlodipine or increasing the dose. This is uncommon but requires immediate medical attention.
When to Contact Your Healthcare Professional
Arrange medical advice if you have:
- Persistent ankle swelling
- Severe dizziness or fainting
- A very fast or irregular heartbeat
- Side effects that interfere with daily life
Seek emergency medical care if you have:
- Chest pain that is severe or worsening
- Difficulty breathing
- Swelling of the face or throat
- Collapse or loss of consciousness
Important Safety Reminder
- Take amlodipine exactly as prescribed.
- Do not stop taking it without speaking to your healthcare professional, as your blood pressure or angina may worsen.
- Tell your doctor or pharmacist about any other medicines or supplements you take, as interactions are possible.
