A Cardiologist Warns: These 5 Types of Medications May Increase the Risk of Heart Attack and Stroke in Some People
Some medications can affect the heart and blood vessels, especially in people who already have cardiovascular risk factors such as high blood pressure, diabetes, high cholesterol, kidney disease, or a history of heart problems. This does not mean these medicines are unsafe for everyone—many are prescribed because their benefits outweigh their risks when used appropriately.
Here are five medication categories that may require extra caution:
1. Certain pain relievers (NSAIDs)
Examples include medicines such as ibuprofen and naproxen.
Why there may be concern:
- Some nonsteroidal anti-inflammatory drugs (NSAIDs), especially at higher doses or with long-term use, may increase blood pressure and may raise the risk of heart attack or stroke in some people.
- Risk may be higher in those with existing heart disease.
Tip: Use the lowest effective dose for the shortest time and ask a healthcare professional if you have heart risk factors.
2. Some decongestants
Examples include medicines containing pseudoephedrine or phenylephrine.
Why there may be concern:
- They can raise blood pressure and increase heart rate.
- They may be risky for people with uncontrolled hypertension or certain heart conditions.
Tip: Check labels on cold and flu products, as some combination medicines contain these ingredients.
3. Certain diabetes medications (depending on the individual situation)
Diabetes itself increases cardiovascular risk, and some medications require careful selection based on a person’s health history.
Why there may be concern:
- The heart safety of diabetes medicines varies widely.
- Some newer medications may actually reduce cardiovascular risk in certain patients, while others may require more careful monitoring.
Tip: Diabetes treatment should be individualized with a healthcare provider.
4. Some hormone-based medications
Certain hormone therapies may affect clotting risk.
Why there may be concern:
- Some estrogen-containing therapies can increase the risk of blood clots, which may contribute to stroke or other cardiovascular events in certain people.
Tip: Discuss personal risk factors such as age, smoking history, and previous clotting problems before starting or continuing hormone therapy.
5. Stimulant medications
Some prescription stimulants can affect the cardiovascular system.
Why there may be concern:
- They may increase heart rate and blood pressure.
- People with certain heart conditions may need additional evaluation and monitoring.
Tip: Regular blood pressure and heart-rate checks may be recommended
