The headline “Eight pills you shouldn’t take because they damage your kidneys” is an oversimplification. Many medications can affect the kidneys, but the risk depends on the drug, the dose, how long it’s taken, your age, your kidney function, and other medical conditions. You should not stop a prescribed medication based on a headline alone.
Some medications that are known to have the potential to harm the kidneys in certain situations include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and diclofenac—especially with frequent use, dehydration, or existing kidney disease.
- Certain antibiotics, including aminoglycosides (such as gentamicin) and, less commonly, some others in susceptible people.
- Some antiviral medications, depending on the specific drug and dose.
- Certain chemotherapy drugs, which are often monitored closely because of kidney risks.
- Lithium, used for bipolar disorder, can affect kidney function with long-term use.
- Some diuretics (“water pills”), particularly if they lead to dehydration or electrolyte problems.
- Certain blood pressure medicines (such as ACE inhibitors or ARBs) can temporarily change kidney function, but they also protect the kidneys in many people, especially those with diabetes or chronic kidney disease. They should not be stopped without medical advice.
- Proton pump inhibitors (PPIs), such as omeprazole, have been associated with certain kidney problems in rare cases, but for many people the benefits outweigh the risks when used appropriately.
To help protect your kidneys:
- Take medications only as directed.
- Stay hydrated, especially during illness or hot weather (unless your clinician has advised fluid restriction).
- Avoid taking multiple NSAIDs at the same time.
- Tell your healthcare provider about all prescription drugs, over-the-counter medicines, and supplements you use.
- If you have kidney disease, diabetes, or high blood pressure, ask your healthcare provider or pharmacist before starting any new medication.
Seek prompt medical care if you develop symptoms such as a marked decrease in urination, swelling of the legs or face, severe weakness, or persistent nausea and vomiting, especially after starting a new medication.
If you have a list of the “eight pills” from the article, paste it here and I can explain which claims are accurate and which may be misleading.
