The 10 Metoprolol Side Effects That Are Often Overlooked

Metoprolol is a useful beta-blocker, but it can cause side effects. Not everyone experiences them, and some symptoms may have causes other than the medication. FDA prescribing information lists several less-obvious reactions. (FDA Access Data)

10 possible effects

1. Unusual fatigue or low energy
2. Dizziness or light-headedness
3. Slow heartbeat (bradycardia)
4. Low blood pressure
5. Cold hands and feet
6. Sleep disturbances or vivid/nightmare-like dreams
7. Depressed mood
8. Confusion or short-term memory difficulties
9. Sexual problems or reduced libido
10. Wheezing or shortness of breath, particularly in susceptible people (FDA Access Data)

Other reported effects include diarrhea, nausea, constipation, dry mouth, rash, itching, blurred vision and tinnitus. Some of these are uncommon, and for several reported reactions a direct cause-and-effect relationship isn’t certain. (FDA Access Data)

⚠️ When to contact your doctor

Get medical advice if you develop fainting, significant dizziness, unusually slow heartbeat, worsening shortness of breath, swelling, or a noticeable deterioration in mood. Metoprolol can also mask some warning symptoms of low blood sugar in people with diabetes. (DailyMed)

❗ Don’t stop it suddenly

If you’re taking metoprolol regularly, don’t abruptly discontinue it without medical guidance. Sudden withdrawal can worsen angina and can increase cardiovascular risk. Your prescriber can decide whether the dose should be reduced gradually or whether another treatment is appropriate. (DailyMed)

Bottom line: Fatigue, dizziness, cold extremities and a slow pulse are among the effects worth watching for. But metoprolol is often prescribed because its cardiovascular benefits are important—so troublesome symptoms should prompt a medication review, not self-discontinuation.