The headline “Eight pills you shouldn’t take because they damage your kidneys” is a common health-warning style claim, but it needs context. Many medications are safe and helpful when taken correctly; the concern is that some drugs can stress the kidneys, especially with high doses, long-term use, dehydration, or in people who already have kidney problems.
Examples of medications that may affect kidney function include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Examples include ibuprofen and naproxen.
- Long-term or excessive use can reduce blood flow to the kidneys and may contribute to kidney injury in some people.
- Certain antibiotics
- Some antibiotics can affect the kidneys, particularly in people with existing kidney disease or when doses are not adjusted properly.
- Some diuretics (“water pills”)
- Used for blood pressure and fluid problems; they can affect kidney function if they cause dehydration or electrolyte changes.
- Certain blood pressure medications
- Some medicines that affect the kidney’s blood flow can change kidney test results, especially when starting treatment or during illness.
- Some heart medications
- Certain drugs require monitoring of kidney function and potassium levels.
- Some acid-reducing medications
- Long-term use of certain acid reflux medicines has been associated in studies with kidney concerns in some populations.
- Lithium
- A medication used for some mental health conditions; long-term use requires monitoring because it can affect kidney function.
- Certain antiviral or chemotherapy medicines
- Some treatments can be hard on the kidneys and are monitored with blood tests.
How to protect your kidneys
- Avoid taking medications—especially painkillers—more often or at higher doses than recommended.
- Tell your healthcare provider about all medicines and supplements you take.
- Stay hydrated, especially during illness or hot weather.
- Get kidney function checked if you use medicines that require monitoring.
Do not stop prescribed medication without speaking with your healthcare professional. The right medication can protect your health, and many kidney-related risks can be managed through proper dosing and monitoring.
