The headline “Eight pills you shouldn’t take because they damage your kidneys” is too broad. Many medicines can affect kidney function in certain circumstances, but you should not stop prescribed medication simply because you see it on a list. Some medicines actually protect the kidneys when used appropriately.
N
NIDDK
+1
8 medicines/categories that deserve particular caution
Ibuprofen and other NSAIDs — regular or high-dose use can cause kidney injury, especially with dehydration, kidney disease, diabetes, or high blood pressure.
N
NIDDK
+1
Naproxen and other NSAIDs — same concern; don’t assume an over-the-counter painkiller is automatically kidney-safe.
N
National Kidney Foundation
Diclofenac and other prescription NSAIDs — prolonged use can be harmful, particularly in people with reduced kidney function.
N
National Kidney Foundation
Celecoxib and other COX-2 inhibitors — these can also affect kidney blood flow and require caution in people at risk of kidney injury.
N
National Kidney Foundation
Lithium — long-term treatment can affect kidney function, so kidney function and lithium levels need appropriate monitoring.
N
National Kidney Foundation
Some antibiotics — certain antibiotics can cause kidney problems or require dose adjustments when kidney function is reduced.
N
NIDDK
Some proton-pump inhibitors (PPIs) — medicines such as omeprazole have been associated with kidney inflammation and kidney injury in some people; this doesn’t mean everyone taking them should stop.
N
National Kidney Foundation
Certain antiviral medicines, such as high-dose acyclovir — kidney toxicity is a recognized concern, particularly with higher doses or susceptible patients.
N
National Kidney Foundation
⚠️ An important exception
ACE inhibitors and ARBs (such as lisinopril or losartan) can change kidney blood tests and potassium levels, but they can also protect the kidneys and slow kidney disease progression in appropriate patients. They shouldn’t be stopped without medical advice.
N
NIDDK
+1
If you have kidney disease, dehydration, vomiting/diarrhea, or take several medicines, ask your doctor or pharmacist to review your complete medication list. Never discontinue a prescribed drug on your own.
N
NIDDK
N
N
Sources
